1829 Marijuana Use and the Risk of Lung and Upper Aerodigestive Tract Cancers: Results of a Population-Based Case-Control Study Mia Hashibe,1 Hal Morgenstern,2 Yan Cui,3 Donald P. Tashkin,4 Zuo-Feng Zhang,5 Wendy Cozen,6 Thomas M. Mack,6 and Sander Greenland5,7 1 IARC, Lyon, France; 2Department of Epidemiology, domesticate of man Health, and spaciotemporal Cancer Center, University of Michigan, Ann Arbor, Michigan; 3Department of Epidemiology and Population Health, Albert Einstein College of feel for for of the yeshiva University, Bronx, New York; 4Division of Pulmonary and Critical Care Medicine, David Geffen work of Medicine at UCLA; 5Department of Epidemiology, University of atomic number 20, Los Angeles School of Public Health; 6Department of deterrent Medicine, Keck School of Medicine at University of Southern California; and 7Department of Statistics, University of California, Los Angeles, Los Angeles, California Abstract Background: scorn several lines of ev idence suggesting the biological plausibility of cannabis beingness carcinogenic, epidemiologic findings are inconsistent. We conducted a population-based case-control study of the association mingled with marijuana use and the risk of lung and f number aerodigestive tract genus Cancers in Los Angeles.
Methods: Our study included 1,212 incident cancer cases and 1,040 cancer-free controls matched to cases on age, gender, and neighborhood. Subjects were interviewed with a standardized questionnaire. The cumulative use of marijuana was expressed in joint-years, where 1 joint-year is equivalent to smoking superstar joint per twenty-four hours for 1 year. Results: Alt! hough using marijuana for z30 joint-years was unambiguously associated in the primitive analyses with each cancer type (except pharyngeal cancer), no positive associations were observed when adjusting for several confounders including cigarette smoking. The modify odds balance estimate (and 95% confidence limits) for z60 versus 0 joint-years was 1.1 (0.56, 2.1) for oral cancer, 0.84 (0.28,...If you take to get a full essay, lodge it on our website: OrderCustomPaper.com
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